منابع مشابه
Sex chromatin of hydatidiform moles.
The placenta is a homograft which is tolerated by the host for an unusually long time. The hydatidiform mole may be said to be even more successful in this respect for it can survive longer and penetrate further in the host even in the absence of a viable foetus. Recent observations that a large number of hydatidiform moles are chromatin positive are of much interest, but so far the reported se...
متن کاملPostmeiotic Sex Chromatin in the Male Germline of Mice
In mammals, the X and Y chromosomes are subject to meiotic sex chromosome inactivation (MSCI) during prophase I in the male germline, but their status thereafter is currently unclear. An abundance of X-linked spermatogenesis genes has spawned the view that the X must be active . On the other hand, the idea that the imprinted paternal X of the early embryo may be preinactivated by MSCI suggests ...
متن کاملUridine-5-h3 Radioautography of the Human Sex Chromatin Body
To obtain an estimate of the rate of RNA synthesis by the heterochromatic sex chromatin body, human female fibroblasts were labeled with uridine-5-H(3) and radioautographed. The number of grains over the sex chromatin body was compared with the number of grains over a comparable area of euchromatin. The ratio was 0.37. When corrected for the higher content of DNA per unit area in heterochromati...
متن کاملTHE EFFECT OF MECHLOROETHAMIN ON RECONSTITUTED CHROMATIN
In this study the effect of a methylated derivative of nitrogen mustard (mechloroethamin) on solubilized and reconstituted chromatin was investigated using UVNis spectroscopy, DNA and SDS gel electrophoresis and densitomeoic scanning techniques, The results indicated that the 210 and 260 nm absorbances of reconstituted chromatin were decreased in a dose-dependent manner after treatment wit...
متن کاملAncestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila
Sex chromosomes evolve distinctive types of chromatin from a pair of ancestral autosomes that are usually euchromatic. In Drosophila, the dosage-compensated X becomes enriched for hyperactive chromatin in males (mediated by H4K16ac), while the Y chromosome acquires silencing heterochromatin (enriched for H3K9me2/3). Drosophila autosomes are typically mostly euchromatic but the small dot chromos...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1967
ISSN: 1468-6244
DOI: 10.1136/jmg.4.3.222-a